Dissecting MENIN in bivalent gene regulation
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Publications — Greenleaf Lab @ Stanford
Epigenetic Modifications of Stem Cells
Full article: Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. - Abstract - Europe PMC
Challenges and opportunities in targeting the menin-MLL interaction. - Abstract - Europe PMC
Mll2 binds to most H3K4me3 promoters, including bivalent promoters. (A)
Rescue strategy for dissecting Mll2 activities in mESC (A) Top panel
Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network: Cell
Functional Classification and Experimental Dissection of Long Noncoding RNAs - ScienceDirect
Cancers, Free Full-Text
Subtype C ALVAC-HIV and bivalent subtype C gp120/MF59 HIV-1 vaccine in low-risk, HIV-uninfected, South African adults: a phase 1/2 trial - The Lancet HIV
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